Pancreatic Enzymes| List and their Function in the digestion

Pancreas is one of the important glands in the our body.

It is an organ located just below the stomach towards the left side opening into duodenum.

It is a dual type of gland i.e. unlike other glands it has both exocrine and endocrine functions.

The endocrine gland part of pancreas secretes hormones like insulin, glucagon etc.

Insulin and glucagon maintain blood glucose levels.

While the exocrine part of it secretes enzymes through pancreatic duct directly into the small intestine.

Pancreatic enzymes:

1. Amylase

2. Trypsin

3. Chymotrypsin

4. Lipase

5. Phospholipase A2

6. Lysophospholipase or phospholipase B

7. Cholesterol esterase.

All of the above enzymes help in digestion of food and then absorption of nutrients.

Amylase: Is the enzyme which breaks down carbohydrates like sucrose, fructose and starch. The end product of this breakdown is glucose which is easily absorbed by gut.

Trypsin & Chymotrypsin: Breaks down proteins from food into peptides and amino acids. These aminoacids are easily absorbed into blood from gut.

Lipase: Helps in breakdown of lipids and fats into fatty acids and glycerol’s for easy absorption.

Phospholipase: They help in breakdown of cell membranes into arachidonic acids.

Phospholipase B: This enzymes cleaves acyl portions of the phospholipids.

Cholesterol esterase: This enzymes catalyzes the cholesterol esters to unesterified cholesterol and free fatty acids.

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