Dipiro Pharmacotherapy a pathophysiologic approach review

Pharmacotherapy is the study of drug use in clinical perspective. Unlike pharmacology where one studies about drugs and their mechanism of action, here one gets a clinical picture of how drug is used.

Being assigned to teach clinical pharmacy and therapeutics subject, i was in search for suitable books to refer to.

I came across a few books like roger walker, g. parathasarathi etc. But they were not to the complete extent.

Then i was suggested to refer to Dipiro Pharmacotherapy a pathophysiologic approach.

I went to library and found it to be a very big and fat book. The pages were smooth and thin.

Then i went through the topic heart failure.

It was so superb to read.

The topic was covered to the complete extent without any points missed.

After such a long experience with teaching using the book, i would recommend anyone to go for it. It is just like a bible for pharmacotherapy. Without this book, the subject of pharmacotherapy will be incomplete.

Dipiro Pharmacotherapy a pathophysiologic approach review

The book covers topic in the following format.

  1. The title or chapter name.
  2. Bullet points
  3. Then introduction to disease
  4. Etiology
  5. Pathophysiology,
  6. Signs & Symptoms.
  7. Diagnosis
  8. Treatment as
    1. Non-Pharmacological if any and then
    2. Pharmacological
  9. Management in different set of patients.
  10. Complications and controversies of treatment.

If you notice the pattern of approach above, it is clear that this book covers every aspect of pharmacotherapy.

The title or chapter names are clear cut an precise. They give an idea of what the internal content could be. For example they do not just mention liver disorders. Instead they have chapters like liver cirrhosis, hepatitis etc. This is because each topic is dealt separately and thoroughly.

Bullet points: These are set of points regarding whole topic under the title. These points include every aspect in concise and short form. This might help us in times of exam revision as one need not go into detail chapter for recap of it. These point include symptoms, cause, types of disease conditions, treatment options etc.

Introduction: In most books introduction gives and idea of disease in few lines. But in this book, it deals a bit more. It gives an idea of percentage population affected by disease in the world, the age group specifically susceptible and also chance of male and female gender variance in terms of disease susceptibility. For example, schizophrenia is said to affect men at their early twenties while for women it is in their early thirties.

Etiology: The etiology is given in possible details so as to have better idea during clinical observations. It covers aspects like life style habits, genetic probability, diet, infections, drug induced and other possibilities. It also mentions the types and differences in the cause and features of the disease.

Pathophysiology: This part of the topic gives an idea of possible changes in anatomy of the organ affected. Presence of any foreign agents, the possible changes in biochemistry of the system involved is mentioned. This helps one learn where the actual problem is and how to correct it.

Signs & Symptoms: The physical and mental signs and symptoms during a disease condition re mentioned quite clearly. Besides the signs related to disorder, any other possible signs due to the disease in the body are also mentioned.

Diagnosis: Diagnosis of disease in clinical perspective is mentioned. This starts from external physical signs to internal pathological changes. It mentions various methods used for proper diagnosis and ascertainment of condition in the patient.

Treatment: This section of the chapter is quite exhaustive in this book. It includes all the possible means like non-pharmacological means and also pharmacological means.

It gives equal weight for both non-pharmacological and pharmacological means of the disease.

Under pharmacological means, it gives the types of medications available, the treatment schedule, dose, dosing schedules and also option to change with progress in the disease conditions.

One can have a clear cut idea of how drugs ar going to be used in as the disease conditions progresses in the patient. IF the disease subsides, it also mentions the steps taken t prevent recurrence and remittance.

Management of different set of patients: This is the key take away from this book in comparison to other books. Different age group of patients requires different set of care and precaution with regards to drug administration. This book deals with this aspect in every disease condition.

It throws light on how to deal with geriatric patient (old age), pregnant women and also babies and infant.

For a medical practitioner, student and even pharmacists, this helps to understand how to use medicines in these kinds of patents with care.

Complications and controversies of treatment: Every treatment and medicine we use have a possibility of complication and controversies. Complications can be like side effects or other damages to the body. While controversies include, that the disease does not subside by particular treatment instead it may aggravate.

This book of dipiro clearly deals with this various aspects of pharmacotherapy.

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