Particle Definition & Importance of Particle Size
Particle is a minute solid material which is formed either due to condensation of fine solid mass or breakage of large solid mass into smaller single entities.
“Particles are the small and discrete fragments of matter which have a tendency to flow and spread.”
They have set of properties which define the nature of whole matter they form or come from.
Particles are of great importance in our daily life as they are part of many products we use.
They are found in the components of medicine, food, cosmetics, chemicals we use in daily life.
Besides they are also part of pollution like air-borne particles from factories, dust particles or pollen from plants etc which can be harmful to us.
These particles are also present in soil and these soil particles decide the type, fertility and also suitability for growth of plants.
All the particles in general have certain properties like electrical, magnetic, chemical and physical characters. Due this they influence the matter they are present in to a large extent.
Particles are classified into different grades based on their particle size. For details on how to measure particle size, read the article Particle size analysis methods.
Lets have a glance into all the probable chances of how particles are involved with us in our daily life.
Importance of Particle Size
In Pharmaceutical industry:
To keep better flow: In filling of capsules or bottles with powder form of drug formulation, the dry material is allowed to flow. The dry powder flows through pipes and reaches the filler. This flow of material depends on particle size and shape.
To maintain precise fill: Filling of powder is done by machine. So definite amount of powder to be filled in each capsule is important to obtain uniform dose in all the capsules. Fixed particle size helps in uniform filling of all capsules.
To control fill rate. The number of capsules made per hour depends on the rate or speed of fill. This rate and speed of fill also depend on the particle size.
To ensure better and compact fill in the space. Presence of gaps or space in the powder after fill lead to porosity and less density resulting in abnormal dose. Precise particle size ensures, unifrom fill with predetermined density.
In other industries.
Foods: Tea powder, coffee powder, salt, pickle powders, condiment powders etc. The smaller is the particle size, the finer is the powder.
Beauty & other skin care items: Talcum powders, prickly heat powders, deodorant and other sprays, lotions, gels have particles in them. These particles decide the consistency of the product, their performance or efficiency, ease of application and time of retention on the skin. For example in a tooth paste, the particle size like those of calcium or silica (silodent) particles decide the teeth polishing ability.
Below is the picture showing micro particles in a bio-glass taken by electron microscope.
Medicine & drug formulations: All the dosage forms like tablets, capsules, solutions, injections, powders etc have medicine or other additives in the form of particles. These particles decide the quantity of the drug in the dose, the stability of the product, its dissolution speed in the body (stomach), the extent of drug absorption into the body and other factors. So particle size is prime importance to a pharmacist.
Nano particles are used for targeted delivery, better absorbtion and also minimize the drug side effects.
Building & other construction material: The particles can also be seen in construction material like sand, ceramics, roof cover like asbestos sheets, glass related items, porcelain etc. The physical properties shape, surface area etc can influence the consistency, durability, cost of the construction etc. For instance sand with fine grade particles is expensive and also gives smooth finish to the walls.
Soil: Particles of soil vary in shape size and other properties. Hence soil can be graded as coarse soil, fine soil, gravel, clay etc. The soil with fine particles is the top most layer and the lower layers of soil have coarser particles.
Electronics: Many components of electronic system like sound systems, memory, circuits have particle in their respective materials they are made of like in magnetic speakers, silica wires etc.
Analytical techniques: Many analytical techniques like HPLC, thin layer chromatography etc have particles in their stationary phase. The efficiency of analysis in these techniques depends on the particle size.
House hold material: Particles are present in most material of home like in kitchen for example water filters, utensils made of porcelain etc, in the making of ceramic tiles, glasses for windows etc.