The Physiology of Height Growth Hormone in the body.
Height growth hormone is also called as human growth hormone (GH).
It is a small protein molecule with 191 amino acids. GH controls growth of a person during his early life. It is believed that the height of a person grows till 18 years and ceases to grow thereafter. GH exerts its action by acting on all the cells and tissues of the body. But more specifically on the bone, cartilage and other cells responsible for body growth in height.
This GH is also called as somatotrophic hormone.
Physiology of human Growth Hormone
GH increases protein deposition by different mechanisms.
1. It enhances the growth of all the cells and tissues of the body which are capable to grow. It promotes the cell size, increased mitosis and increase in number and differentiation of bone and muscle cells.
2. It increases the rate of protein synthesis by
a) Enhances the DNA transcription to form mRNA responsible for protein formation.
b) Increase the translocation of RNA for enhanced protein synthesis.
C) Enhanced amino acids transport across the cell membrane.
d) Decreases of protein catabolism by mobilization of fatty acids required of gluconeogenesis. Thus amino acids are spared.
3. Increase fat metabolism and thereby lean body mass.
GH promotes release of fatty acids from adipose tissue. Then it also enhances the utilization of fatty acid for energy generation. Thus the with its ability to enhance fat metabolism and protein deposition, it causes lean body mass.
However, it is effective in height growth till particular age of 18. This height growth stops at around 18 years of age due to growth of pubic symphisis. During this phase, epiphysis of the long bones unites with the shafts. Once done no further rise in height is possible.
So growth in height is freely possible till this age of 18 to 19. There after though the growth hormone is secreted, there is no growth in height. Instead, the body tissue mass grows.
So the best chance of height growth by this hormone is before the end of height growth.
Can one grow taller after puberty? Puberty is physical maturation around 13-15 years for both girls and boys. And the age till which body grows in height is 18 years. So one has chances of growth for 4-5years after puberty.